US Patent Issued to Hoffmann-La Roche on June 17 for "Optimized method for antibody capturing by mixed mode chromatography" (German, Japanese Inventors)

ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,075, issued on June 17, was assigned to Hoffmann-La Roche Inc..

"Optimized method for antibody capturing by mixed mode chromatography" was invented by Roberto Falkenstein (Munich), Thorsten Lemm (Kochel am See, Germany), Markus Strasser (Penzberg, Germany) and Hidenari Yamada (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "Herein is reported a method for the purification of an antibody directly captured from clarified cell culture supernatants using Streamline CST and/or Capto MMC, wherein especially product related (aggregates and fragments) and process related impurities (host cell protein, media components) could efficiently be removed, res...