ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,687, issued on July 22, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Benzodiazepine derivatives as GABA a gamma 1 PAM" was invented by Bjoern Bartels (Schopfheim, Germany), Giuseppe Cecere (Basel, Switzerland), Guido Galley (Rheinfelden, Germany), Luca Gobbi (Buus, Switzerland), Maria-Clemencia Hernandez (Delemont, Switzerland), Andreas Koblet (Bottmingen, Switzerland), Andres Miguel Olivares Morales (Binningen, Switzerland), Angelique Patiny-Adam (Kembs, France) and Valerie Runtz-Schmitt (Rixheim, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides novel heterocyclic compounds having the general formula (I)...