US Patent Issued to Hoffmann-La Roche on Jan. 20 for "Multispecific antibody screening method using recombinase mediated cassette exchange" (German Inventor)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,529,050, issued on Jan. 20, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).

"Multispecific antibody screening method using recombinase mediated cassette exchange" was invented by Ulrich Goepfert (Penzberg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "Herein is reported a method for preparing a recombinant host cell library expressing bispecific antibodies using targeted integration into a host cell comprising an exogenous nucleotide sequence integrated at a site within a locus of the genome of the host cell, wherein the exogenous nucleotide sequence comprises a first and a second recombination recognition sequence flanking at leas...