ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,528,784, issued on Jan. 20, was assigned to HOFFMANN-LA ROCHE INC. (Little Falls, N.J.).

"Alkynyl-(heteroaryl)-carboxamide HCN1 inhibitors" was invented by Bjoern Bartels (Schopfheim, Germany), Amanda Lee Dupont (Riehen, Switzerland), Benjamin J. Hall (Copenhagen, Denmark), Jean-Yves Wach (Basel, Switzerland), Christian Schnider (Biel-Benken, Switzerland), Patrick Schnider (Bottmingen, Switzerland), Michael Reutlinger (Freiburg, Germany), Eoin O'Connor (Basel, Switzerland), Eva Katrin Harde (Basel, Switzerland) and Michael Weber (Sissach, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compounds of formula Iwher...