ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,637, issued on Jan. 13, was assigned to HOFFMANN-LA ROCHE INC. (Little Falls, N.J.).
"Complement factor based affinity chromatography" was invented by Alexander Knaupp (Wackersberg, Germany), Laurent Lariviere (Munich), Petra Rueger (Penzberg, Germany), Tilman Schlothauer (Penzberg, Germany) and Stefan Seeber (Penzberg, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "Herein is reported a fusion polypeptide according to formula I (TAG-X1-C1qA-X2-C1qB-X3-C1qC-X4), comprising a fragment of SEQ ID NO: 01 (C1qA), a fragment of SEQ ID NO: 03 (C1qB), a fragment of SEQ ID NO: 05 (C1qC) and optionally a tag (TAG)."
The patent was filed on June 27, 20...