ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,307, issued on April 22, was assigned to Hoffmann-La Roche Inc. (Little Falls, N.J.).
"Oligomers and oligomer conjugates" was invented by Hassan Javanbakht (Basel, Switzerland), Soren Ottosen (Glostrup, Denmark) and Morten Lindow (Copenhagen, Denmark).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an oligomer conjugate for use in the treatment of a viral disorder. The oligomer conjugate comprises: a) an oligomer capable of modulating a target sequence in HBx and/or HBsAg of Hepatitis B Virus (HBV) to treat said viral disorder; and b) a carrier component capable of delivering the oligomer to the liver which is linked, p...