ALEXANDRIA, Va., June 16 -- United States Patent no. 12,303,525, issued on May 20, was assigned to HOFFMAN-LA ROCHE INC. (Little Falls, N.J.).

"Nucleic acid molecule for reduction of PAPD5 and PAPD7 mRNA for treating hepatitis B infection" was invented by Susanne Kammler (Horsholm, Denmark), Anais Lopez (Basel, Switzerland), Henrik Mueller (Basel, Switzerland), Soren Ottosen (Horsholm, Denmark) and Lykke Pedersen (Horsholm, Denmark).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to nucleic acid molecules that are complementary to both PAP associated domain containing 5 (PAPD5) and PAP associated domain containing 7 (PAPD7), leading to inhibition of the expression of both PAPD5 an...