ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,521,450, issued on Jan. 13, was assigned to Hitachi Ltd. (Tokyo).

"DNA, expression vector, transcript, cell, pharmaceutical composition, and medicine" was invented by Atsushi Okuma (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "An object of the invention is to provide a novel pharmaceutical composition. The pharmaceutical composition of the disclosure contains a DNA encoding a suicide gene having at least one intron sequence. The intron sequence has a donor sequence or an acceptor sequence to be used in a tumor cell with abnormal splicing not in a normal cell. In a transcript of the DNA, the suicide gene is expressed when the intron is abnormally...