ALEXANDRIA, Va., June 10 -- United States Patent no. 12,290,653, issued on May 6, was assigned to HISAMITSU PHARMACEUTICAL Co. INC. (Tosu, Japan).

"Microneedle sheet production method and microneedle sheet" was invented by Eisuke Hatanaka (Tsukuba, Japan), Kazuki Kuriyama (Tsukuba, Japan) and Naoki Yamamoto (Tsukuba, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of producing a microneedle sheet according to an embodiment includes: preparing a sheet having a first surface and a second surface; making a first cut in a range from the first surface to the second surface of the sheet to form a first outer edge that defines a tip end of the microneedle; and making, after forming the first outer edg...