ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,180, issued on July 15, was assigned to Hiroshima University (Hiroshima, Japan).
"Polypeptide containing DNA-binding domain" was invented by Takashi Yamamoto (Kure, Japan), Tetsushi Sakuma (Higashihiroshima, Japan), Hiroshi Ochiai (Higashihiroshima, Japan), Shinya Matsuura (Hiroshima, Japan) and Tatsuo Miyamoto (Hiroshima, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides an artificial nuclease comprising a DNA-binding domain and a function domain linked to each other via a polypeptide consisting of 35 to 55 amino acid residues wherein amino acid residues at two sites in a DNA-binding module contained in a DNA-bindi...