US Patent Issued to Harpoon Therapeutics on Sept. 16 for "Binding moiety for conditional activation of immunoglobulin molecules" (California Inventors)

ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,860, issued on Sept. 16, was assigned to Harpoon Therapeutics Inc. (South San Francisco, Calif.).

"Binding moiety for conditional activation of immunoglobulin molecules" was invented by Shuoyen Jack Lin (San Bruno, Calif.), Richard J. Austin (San Francisco), Bryan D. Lemon (Mountain View, Calif.), Kathryn Kwant (San Bruno, Calif.), Sony S. Rocha (San Francisco) and Holger Wesche (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are binding moieties that comprise non-CDR loops for masking the binding of a binding molecule to its target and CDRs for binding bulk serum proteins. Conditionally active target binding proteins...