ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,504, issued on July 29, was assigned to Harpoon Therapeutics Inc. (South San Francisco, Calif.).
"Trispecific proteins and methods of use" was invented by Holger Wesche (San Francisco), Bryan D. Lemon (Mountain View, Calif.) and Richard J. Austin (San Francisco).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are B cell maturation agent (BCMA) targeting trispecific proteins comprising a domain binding to CD3, a half-life extension domain, and a domain binding to BCMA. Also provided are pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such BCMA targeting trispecific ...