ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,865, issued on Jan. 13, was assigned to Harbinger Health Inc. (Cambridge, Mass.).
"Nucleic acid enrichment method" was invented by Anthony P. Shuber (Northbridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides methods of detecting genetic features that only require a single successful interrogation. A sample that includes nucleic acid may have a first set of adaptors ligated to free ends in a manner that is not target specific. Then, a reagent such as a Cas endonuclease is used to cut nucleic acid molecules that contain a target of interest, leaving a cut end. A second adaptor type is attached to the cut end(s) and provi...