ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,477, issued on Jan. 27, was assigned to HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL Co. LTD. (Zhejiang, China).

"Compound having KHK inhibitory effect" was invented by Zhixiang Pan (Shanghai), Haiying He (Shanghai), Zhigan Jiang (Shanghai), Jianhua Xia (Shanghai), Lei Zhang (Shanghai), Chen Zhang (Shanghai), Jian Li (Shanghai) and Shuhui Chen (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "A compound having a KHK inhibitory effect, or pharmaceutically acceptable salts thereof, and use thereof in the preparation of a medicament for treating a disease associated with KHK kinase abnormal expression. Provided is a compound as represented by formula...