ALEXANDRIA, Va., June 16 -- United States Patent no. 12,304,967, issued on May 20, was assigned to HANGZHOU SUMGEN BIOTECH Co. LTD. (Hangzhou, China) and SUMGEN MAB (BEIJING) BIOTECH Co. LTD. (Beijing).
"Fusion protein and use thereof" was invented by Ming Lv (Hangzhou, China), Xiaoran Ding (Hangzhou, China), Shiwei Miao (Hangzhou, China), Bin Tan (Hangzhou, China) and Xuegong Wang (Hangzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a fusion protein, comprising a first binding domain that specifically binds a tumor-associated antigen, and a second binding domain that specifically binds a CD47 protein, wherein the second binding domain comprises a mutant of a human SIRPAlpha variant 1....