ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,187, issued on Aug. 5, was assigned to Hangzhou Normal University (Hangzhou, China).

"Selenium-containing nano HOF, antioxidant nanozyme, preparation method and application thereof" was invented by Junqiu Liu (Hangzhou, China), Ruizhen Tian (Hangzhou, China), Yijia Li (Hangzhou, China) and Jiayun Xu (Hangzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "A multi-enzyme cascade antioxidant nano HOF and preparation method and application thereof are provided. The present invention discloses a nano HOF based on selenium-containing ligand for the first time, the nano HOF does not contain metal and has good biocompatibility, which is a universal l...