ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,539,353, issued on Feb. 3, was assigned to HANGZHOU HUIBO SCIENCE AND TECHNOLOGY Co. LTD (Hangzhou, China).

"Efficient biphasic calcium phosphate coating method" was invented by Gang Wu (Zhejiang, China), Liyong Wu (Zhejiang, China) and Yunyu Lu (Zhejiang, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "An efficient biphasic calcium phosphate coating method. A high-concentration (4.5x) supersaturated calcium phosphate solution (SCPS) is used for coating and a thicker continuous coating is formed on a titanium disc. The coating contains dicalcium phosphate dihydrate and hydroxyapatite. The coating has improved encapsulation efficiency of a protein FI...