ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,415,784, issued on Sept. 16, was assigned to Handa Oncology LLC (San Jose, Calif.).

"Cabozantinib compositions and methods of use" was invented by Fang-Yu Liu (San Jose, Calif.), K.C. Sung (Tainan, Taiwan), Yu Zhang (Hangzhou, China), Shang Wei Qin (Hangzhou, China), John Duan (Tainan, Taiwan) and George Kraft (San Jose, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to oral compositions comprising cabozantinib salts and at least one pharmaceutically acceptable excipient and methods of using the oral compositions to increase the oral bioavailability of the cabozantinib and reduce the adverse events associate with th...