US Patent Issued to HALOZYME on July 29 for "PH20 polypeptide variants with a modification at position 324 of the PH20 polypeptide and a method of making thereof" (California, Oregon Inventors)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,685, issued on July 29, was assigned to HALOZYME INC. (San Diego).

"PH20 polypeptide variants with a modification at position 324 of the PH20 polypeptide and a method of making thereof" was invented by Ge Wei (San Diego), H. Michael Shepard (Eugene, Ore.), Qiping Zhao (San Diego) and Robert James Connor (Oceanside, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof."

The patent was filed on June 23, 2023, under Application No. 18/340,78...