ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,602, issued on Nov. 11, was assigned to H4 ORPHAN PHARMA (Dijon, France) and Gaetan Terrasse (Dijon, France).
"Use of an opioid molecule for treating dry eye and eyes suffering from allergies" was invented by Gaetan Terrasse (Dijon, France) and Catherine Bur (Dijon, France).
According to the abstract* released by the U.S. Patent & Trademark Office: "The use of an opioid molecule, the levorotatory and dextrorotatory enantiomers of (3S)-6,7-dimethoxy-3-[(5R)-4-methoxy-6-methyl-7,8-dihydro-5H-[1,3] dioxolo [4,5-glisoquinolin-5-yl]-3H-2-benzofuran-1-one, capable of CFTR modulation and of suppressing the degranulation of basophils and mast cells, for the treatment of dry eye and eyes ...