ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,626, issued on March 25, was assigned to Guardant Health Inc. (Palo Alto, Calif.).
"Methods and systems for detecting genetic variants" was invented by Amirali Talasaz (Atherton, Calif.), Helmy Eltoukhy (Atherton, Calif.) and Stefanie Ann Ward Mortimer (Morgan Hill, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein in are methods and systems for determining genetic variants (e.g., copy number variation) in a polynucleotide sample. A method for determining copy number variations includes tagging double-stranded polynucleotides with duplex tags, sequencing polynucleotides from the sample and estimating total number of polynucleot...