US Patent Issued to Guardant Health on Feb. 3 for "Identification of somatic mutations versus germline variants for cell-free DNA variant calling applications" (California Inventors)

ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,540,351, issued on Feb. 3, was assigned to Guardant Health Inc. (Palo Alto, Calif.).

"Identification of somatic mutations versus germline variants for cell-free DNA variant calling applications" was invented by Bahram Ghaffarzadeh Kermani (Los Altos, Calif.) and Helmy Eltoukhy (Atherton, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides systems and methods to detect somatic or germline variants by providing a predetermined genomic DNA (gDNA) to an assay mixture, and capturing a sample of a subject's genetic information using a DNA sequencer and detecting genetic variants from the genetic information. A mutation may the...