ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,540,130, issued on Feb. 3, was assigned to GRUENENTHAL GMBH (Aachen, Germany).

"Substituted pyrrolidine amides IV" was invented by Florian Jakob (Aachen, Germany), Jo Alen (Averbode, Belgium), Sebastian Krueger (Aachen, Germany), Daniela Friebe (Duesseldorf, Germany) and Stephanie Hennen (Aachen, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to compounds according to general formula (I),which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor."

The patent was filed on Dec. 17, 2021, under Appl...