US Patent Issued to Grifols Worldwide Operations on Nov. 25 for "Method for obtaining Alpha-1 proteinase inhibitor" (North Carolina Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,907, issued on Nov. 25, was assigned to Grifols Worldwide Operations Ltd. (Dublin).

"Method for obtaining Alpha-1 proteinase inhibitor" was invented by James Rebbeor (Research Triangle Park, N.C.), Jeffrey A. Yuziuk (Research Triangle Park, N.C.), George Grady (Research Triangle Park, N.C.) and Dennis McBride (Research Triangle Park, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for obtaining Alpha-1 Proteinase Inhibitor for obtaining highly-concentrated Alpha-1 Proteinase Inhibitor (A1PI) includes preparing a solution of A1PI by concentrating an initial solution of A1PI by tangential flow filtration (TFF) against water. The final con...