ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,669, issued on Nov. 11, was assigned to GRANDER ACQUISITION LLC (Boca Raton, Fla.).

"Methods for development and use of minimally polarized function cell micro-aggregate units in tissue applications using LGR4, LGR5, and LGR6 expressing epithelial stem cells" was invented by Denver M. Lough (Salt Lake City).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are constructs of micro-aggregate multicellular, minimally polarized grafts containing Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, med...