US Patent Issued to Grand Decade Developments on Nov. 25 for "Plasmid constructs for treating cancer and methods of use" (California Inventors)

ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,918, issued on Nov. 25, was assigned to Grand Decade Developments Ltd. (Hong Kong, Hong Kong).

"Plasmid constructs for treating cancer and methods of use" was invented by Christopher Twitty (San Diego), Anandaroop Mukhopadhyay (San Diego), David A. Canton (San Diego), Mia Han (San Diego) and Erica Browning (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described are expression cassettes encoding CD3-half-BiTE, CXCL9 and CTLA-4 scFv. The described expression cassettes can be used to treat cancer in a subject. Methods of delivering the expression cassettes to a tumor by direct intratumoral injection and electroporation are also described."...