ALEXANDRIA, Va., Feb. 26 -- United States Patent no. 12,237,053, issued on Feb. 25, was assigned to GRAIL Inc. (Menlo Park, Calif.).
"Detecting cross-contamination in sequencing data" was invented by Onur Sakarya (Redwood City, Calif.) and John Lamping (Los Altos, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Detecting cross-contamination between test samples used for determining cancer in a subject is beneficial. To detect cross-contamination, test sequences including at least one single nucleotide polymorphism are prepared using genome sequencing techniques. Some of the test sequences can be filtered to improve accuracy and precision. A prior contamination probability for each test sequence is dete...