ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,503,432, issued on Dec. 23, was assigned to Global Life Sciences Solutions Canada ULC (Vancouver, Canada).
"Ionizable lipids for nucleic acid delivery" was invented by Nikita Jain (Vancouver, Canada), Anitha Thomas (New Westminster, Canada) and Andrew William Brown (Vancouver, Canada).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present document describes compounds, or pharmaceutically acceptable salt thereof, of a core formula (I) where R1 features an amine group, particularly useful in the formulation of lipid particles including nucleic acid therapeutic agents, or proteins, or both, and for delivery of nucleic acid and protein therapeutics to ce...