US Patent Issued to GlaxoSmithKline Biologicals on Oct. 14 for "Process for the manipulation of nucleic acids" (Swiss Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,442,019, issued on Oct. 14, was assigned to GlaxoSmithKline Biologicals SA (Rixensart, Belgium).

"Process for the manipulation of nucleic acids" was invented by Amirreza Faridmoayer (Schlieren, Switzerland), Michael Thomas Kowarik (Schlieren, Switzerland), Gerd Martin Lipowsky (Schlieren, Switzerland) and Fabio Serventi (Schlieren, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "A process for engineering a host cell comprising the steps of a) integrating a first polynucleotide cassette including a first selection marker flanked by a first pair of recombination sites; b) removing the first selection marker by the action of a recombinase which ...