US Patent Issued to GLAXOSMITHKLINE BIOLOGICALS on Aug. 12 for "Modified cytomegalovirus proteins and stabilized complexes" (Maryland, Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,384,819, issued on Aug. 12, was assigned to GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium).

"Modified cytomegalovirus proteins and stabilized complexes" was invented by Enrico Malito (Rockville, Md.), Matthew James Bottomley (Rockville, Md.), Andrea Carfi (Cambridge, Mass.), Sumana Chandramouli (Rockville, Md.) and Kate Luisi (Rockville, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described are mutant human cytomegalovirus (HCMV) pentamer complex polypeptides, methods of making them, and their use in HCMV protein complexes and compositions. In particular, the use of the modified HCMV polypeptides to stabilize HCMV complexes or unmask a penta...