ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,162, issued on Aug. 26, was assigned to Geron Corp. (Foster City, Calif.).
"Guanine analogs as telomerase substrates and telomere length affectors" was invented by Sergei M. Gryaznov (San Mateo, Calif.), Ronald A. Pruzan (Palo Alto, Calif.) and Krisztina Pongracz (Oakland, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to compounds useful for inhibiting telomere elongation. More specifically, the invention provides nucleotide analogs that are incorporated into telomeres by telomerase thereby inhibiting elongation of telomeres. The compounds are use in treating cancer and other cell proliferative diseases."
The patent w...