US Patent Issued to Georgia State University Research Foundation on April 22 for "Treatment of aneurysms" (Georgia Inventor)

ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,047, issued on April 22, was assigned to Georgia State University Research Foundation Inc. (Atlanta).

"Treatment of aneurysms" was invented by Ming-Hui Zou (Atlanta).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods for detecting and/or treating a subject having an aneurysm or at risk for developing an aneurysm. It has been discovered that a key metabolite of the kynurenine (Kyn) pathway, a major route for the metabolism of essential amino acid tryptophan (Trp) into nicotinamide adenine dinucleotide (NAD+), plays a critical role in the formation of aneurysms, for example abdominal aortic aneurysms. In particular, it...