US Patent Issued to Genzyme on Nov. 11 for "Enhanced delivery of viral particles to the striatum and cortex" (Massachusetts, New Jersey Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,657, issued on Nov. 11, was assigned to Genzyme Corp. (Cambridge, Mass.).

"Enhanced delivery of viral particles to the striatum and cortex" was invented by Lisa M. Stanek (Bridgewater, N.J.) and Lamya S. Shihabuddin (West Newton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are novel methods for delivering recombinant adeno-associated viral (rAAV) particles to the central nervous system of a mammal (e.g., a human). In aspects, the methods involve administering rAAV particles containing a heterologous nucleic acid to the striatum and causing expression of the heterologous nucleic acid in at least the cerebral cortex and the st...