ALEXANDRIA, Va., June 19 -- United States Patent no. 12,331,296, issued on June 17, was assigned to Genzyme Corp. (Cambridge, Mass.).
"Variant RNAi" was invented by Catherine R. O'Riordan (Cambridge, Mass.), Adam Palermo (Cambridge, Mass.), Brenda Richards (Cambridge, Mass.) and Lisa M. Stanek (Cambridge, N.J.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are RNAi molecules for treating Huntington's disease. Further provided herein are expression cassettes, vectors (e.g., rAAV, recombinant adenoviral, recombinant lentiviral, and recombinant HSV vectors), cells, viral particles, and pharmaceutical compositions containing the RNAi. Yet further provided herein are methods and kits related to th...