ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,491,177, issued on Dec. 9, was assigned to GENVARA BIOPHARMA INC. (Westminster, Colo.).

"Methods and compositions involving bucindolol for the treatment of atrial fibrillation" was invented by Michael Bristow (Englewood, Colo.) and Christopher Dufton (Englewood, Colo.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The current methods and compositions relate to treatment of atrial fibrillation with bucindolol in patients, including patients with heart failure, after being determined to be homozygous Arg389 in the Beta1 adrenergic receptor gene."

The patent was filed on Jan. 6, 2023, under Application No. 18/150,993.

*For further information, including i...