US Patent Issued to Gentium on Jan. 20 for "Euglobulin-based method for determining the biological activity of defibrotide" (Italian, Swiss Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,529,052, issued on Jan. 20, was assigned to Gentium S.R.L. (Villa Guardia, Italy).

"Euglobulin-based method for determining the biological activity of defibrotide" was invented by Terenzio Ignoni (Solbiate, Italy), Vijay Kumar (Casnate, Italy) and Khalid Islam (Massagno, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "It is disclosed a method for determining the biological activity of defibrotide, which comprises the steps of: a) bringing into contact defibrotide, mammalian euglobulin and a substrate specific for the plasmin which, by reaction with the plasmin, provides a measurable product; and b) measuring the amount of product formed at su...