ALEXANDRIA, Va., June 25 -- United States Patent no. 12,338,289, issued on June 24, was assigned to GENMAB B.V. (Utrecht, Netherlands).
"Antibody variant combinations and uses thereof" was invented by Rob De Jong (Utrecht, Netherlands), Frank Beurskens (Utrecht, Netherlands), Simone Oostindie (Utrecht, Netherlands), Aran Frank Labrijn (Nigtevecht, Netherlands), Kristin Strumane (Werkhoven, Netherlands), Janine Schuurman (Diemen, Netherlands) and Bart-Jan De Kreuk (Utrecht, Netherlands).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are combinations of first and second antibodies having modified Fc effector functions resulting from amino acid substitutions in the Fc region, the amino acid subst...