ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,816, issued on July 8, was assigned to GENETHON (Evry, France) and CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris).
"CNS gene delivery using peripheral administration of AAV vectors" was invented by Martine Barkats (Charenton-le-pont, France).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compositions and methods for the delivery of therapeutic proteins to the CNS using recombinant AAV vectors. More specifically, the invention relates to compositions and methods for delivering proteins into the cerebrospinal fluid of mammalian subjects through peripheral administration of AAV vectors. The invention may be used to ...