US Patent Issued to Generation Bio on Oct. 14 for "Closed-ended DNA vectors obtainable from cell-free synthesis and process for obtaining ceDNA vectors" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,442,015, issued on Oct. 14, was assigned to Generation Bio Co. (Cambridge, Mass.).

"Closed-ended DNA vectors obtainable from cell-free synthesis and process for obtaining ceDNA vectors" was invented by Ozan Alkan (Cambridge, Mass.), Robert Michael Kotin (Cambridge, Mass.), Matthew Stanton (Cambridge, Mass.), Douglas Anthony Kerr (Cambridge, Mass.) and Carolyn Pelletier (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The application describes methods for synthetic synthesis and cell-free synthesis of DNA vectors, particularly closed-ended DNA vectors (e.g., ceDNA vectors) having linear and continuous structure for delivery and expression...