ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,299, issued on Sept. 23, was assigned to GENENTECH INC. (South San Francisco, Calif.).
"Expression of FC-containing proteins" was invented by Benjamin Haley (San Francisco), Zhilan Hu (Foster City, Calif.), John C. Joly (San Mateo, Calif.), Amy Y. Shen (San Mateo, Calif.) and Bradley Richard Snedecor (Portola Valley, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides compositions comprising a Fc-containing protein wherein substantially all the Fc domains have a C-terminal lysine. Further provided are host cell for producing said compositions, methods of making said host cells and compositions, and method of use the...