US Patent Issued to Genentech on May 13 for "Bispecific antigen-binding molecules and methods of use" (California Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,270, issued on May 13, was assigned to Genentech Inc. (South San Francisco, Calif.).

"Bispecific antigen-binding molecules and methods of use" was invented by Diego Ellerman (San Francisco), Teemu T. Junttila (San Mateo, Calif.), Twyla Noelle Lombana (San Francisco), Dionysos Slaga (Richmond, Calif.) and Christoph Spiess (Mountain View, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides bispecific antigen-binding molecules having a monovalent arm specific to a first target antigen (e.g., a T cell antigen, such as CD3) and a bivalent arm specific for a second target antigen (e.g., a tumor antigen, such as HER2). Bisp...