US Patent Issued to Genentech on Jan. 20 for "Prevention of disulfide bond reduction during recombinant production of polypeptides" (California Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,528,875, issued on Jan. 20, was assigned to Genentech Inc. (South San Francisco, Calif.).

"Prevention of disulfide bond reduction during recombinant production of polypeptides" was invented by Yung-Hsiang Kao (San Mateo, Calif.), Michael W. Laird (San Ramon, Calif.), Melody Trexler Schmidt (Danville, Calif.), Rita L. Wong (Redwood City, Calif.) and Daniel P. Hewitt (Sunnyvale, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention concerns methods for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduc...