ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,408, issued on May 27, was assigned to GammaDelta Therapeutics Ltd (London) and F-star Therapeutics Ltd. (Cambridge, Great Britain).
"Multispecific anti-TCR delta variable 1 antibodies" was invented by Mihriban Tuna (Cambridge, Great Britain), Mark Uden (London), Joshua Freedman (London) and Natalie Mount (London).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides multispecific antibodies comprising a Fab region and an Fc region, wherein the Fab region comprises a binding site specific for an epitope of the variable delta 1 (VDelta1) chain of a GammaDelta T cell receptor (TCR); and the Fc region comprises an EGFR binding si...