ALEXANDRIA, Va., March 19 -- United States Patent no. 12,252,594, issued on March 18, was assigned to Galderma Holding SA (Zug, Switzerland).
"Method of preparing a hydrogel product" was invented by Lars Nord (Uppsala, Sweden), Hotan Mojarradi (Uppsala, Sweden) and Johan Olsson (Bromma, Sweden).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method of preparing a hydrogel product comprising crosslinked glycosaminoglycan molecules, comprising the steps of: (a) providing a mixed solution of glycosaminoglycan molecules, a di- or multinucleophilic functional crosslinker, and a mononucleophilic functional graft chain; (b) activating carboxyl groups on the glycosaminoglycan molecules with a coupling agent to form ...