US Patent Issued to Freenome Holdings on Oct. 28 for "Methods and systems for high-depth sequencing of methylated nucleic acid" (California Inventors)

ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,724, issued on Oct. 28, was assigned to Freenome Holdings Inc. (Brisbane, Calif.).

"Methods and systems for high-depth sequencing of methylated nucleic acid" was invented by Eric Ariazi (Redwood City, Calif.), David Weinberg (San Francisco), Greg Hogan (San Francisco), John St. John (Brisbane, Calif.) and Michael Pearson (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and systems provided herein address current limitations of bisulfite-based methylation sequencing by improving the quality and accuracy of nucleic acid methylation sequencing and uses thereof for detection of disease. Methods that include minimally-destructive con...