ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,312, issued on July 8, was assigned to FRED HUTCHINSON CANCER CENTER (Seattle).

"Methods for improving adoptive cell therapy" was invented by Stanley R. Riddell (Sammamish, Wash.) and Shivani Srivastava (Seattle).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides reagents and methods for treating disease using modified immune cells (e.g., T cell comprising CAR or TCR) in combination with an agent associated with induction of immunogenic cell death (ICD) and optionally further in combination with an agent that specifically binds to and/or inhibits an immune suppression component and/or an agonist of an immune stimulatory mol...