US Patent Issued to Fred Hutchinson Cancer Center on July 8 for "Engineered trimeric CD70 proteins and uses thereof" (Washington Inventors)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,618, issued on July 8, was assigned to Fred Hutchinson Cancer Center (Seattle).

"Engineered trimeric CD70 proteins and uses thereof" was invented by Carla A. Jaeger (Seattle), Colin E. Correnti (Seattle) and Stanley R. Riddell (Sammamish, Wash.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Engineered trimeric CD70 proteins for use in ex vivo T cell manufacturing are described. Use of the proteins during manufacturing creates expanded T cell populations with enhanced properties such as earlier proliferation in culture; selective expansion of nave and memory T cell subsets; longer persistence in vivo following administration to a subject; and improved...