ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,335, issued on March 25, was assigned to Foresee Pharmaceuticals USA Inc. (Newark, Del.).
"Matrix metalloproteinase (MMP) inhibitors and methods of use thereof" was invented by Wenjin Yang (Newark, Del.), Kai-Wei Chang (Newark, Del.), Suying Liu (Newark, Del.) and Cheng-Han Tsai (Newark, Del.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Hydantoin based compounds useful as inhibitors of matrix metalloproteinases (MMPs), particularly macrophage elastase (MMP-12) are described. Also described are related compositions and methods of using the compounds to inhibit MMP-12 and treat diseases mediated by MMP-12, such as asthma, chronic obstructive pulmon...