ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,453, issued on Dec. 30, was assigned to FOGHORN THERAPEUTICS INC. (Cambridge, Mass.).

"BRM/BRG1 inhibitors and uses thereof" was invented by Neville John Anthony (Northborough, Mass.), Rishi G. Vaswani (Lexington, Mass.), David Simon Millan (Stow, Mass.) and Shawn E. R. Schiller (Haverhill, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The compounds disclosed herein may be inhibitors of BRG1 (Brahma-related gene-1) and/or BRM (Brahma). The compounds or pharmaceutically acceptable salts thereof are useful for the treatment of disorders associated with an alteration in a BAF complex, e.g., a disorder associated with an alteration in one or both...