ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,947, issued on April 15, was assigned to FIOS THERAPEUTICS LLC (Rochester, Minn.).

"Viable genetically modified sheep with an inactivated alpha-1,3-galactosyltransferase (GGTA1) gene" was invented by Christopher G. A. McGregor (Rochester, Minn.), Irina Polejaeva (Logan, Utah) and Guerard Byrne (Minneapolis).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is the first viable galactosyltransferase (Gal) knock-out sheep having a deletion or mutation of alpha-1,3-galactosyltransferase (GGTA1) gene and methods of making the same. Also provided are methods of screening a biological implant for stimulation of an antibody-mediated inflammatory ...